Kinesin Nomenclature - Table 1

 

 

Standardized Kinesin Nomenclature

Further information regarding the new standardized system of kinesin nomenclature (Lawrence et al., 2004) is shown below. Original protein names are retained but new names have been given to the kinesin groups or families. New and former names of the kinesin families with examples of the proteins they include are shown in the table below.

 

Archived Web Discussion          Problems with Previous Nomenclature Systems

 

 

Table 1.  Standardized names for each kinesin family (from the JCB manuscript).

 

Standardized

Name

Example

Sequences a

Other Names for this Group of Sequencesb

Endow et al.  c

HirokawaIdIII        

Lawrence et al. e

Other NamesI

 

 

 

 

 

 

Kinesin-1

KHC (J05258)

KIF5A (AF067179)

KHC (L47106)

K7 (U41289)

KHC

N-I

Kinesin-I

Conventional

Kinesin-2

KRP85 (L16993)

KRP95 (U00996)

KIF3A (D12645)

KIF3B (D26077)

FLA10 (L33697)

KRP85/95

N-IV

Kinesin-II

Heterotrimeric

Kinesin-3

KIF1A (D29951)

UNC104 (M58582)

KIN (L07879)

Unc104 (AF245277)

Unc-104/Kif1

N-III

Unc104

Monomeric

Kinesin-4

KIF4 (D12646)

CHRKIN (U18309)

XKLP1 (X82012)

F11C1.80 (AB061676)

AY224568 (AY224568)

K8 (U69985)

Chromokinesin/Kif4

N-V

Chromokinesin (upper clade)

 

Kinesin-5

KIF11 (AB001427)

EG5 (X54002)

BIMC (M32075)

KRP125 (AC005896)

BimC

N-II

BIMC

Eg5

Bipolar

Tetrameric

Kinesin-6

MKLP1 (X67155)

KIF20A (NM_009004)

K12 (AY484465)

MKLP1

N-VI

MKLP

(lower clade)

Cho1

Kinesin-7

CENP-E (Z15005)

KIF10 (AB001426)

KIP2p (Z11963)

AB028470 (AB028470)

CENP-E

 

N-VII

CENP-E

 

Kinesin-8

KIF19A (AB054026)

KIP3p (Z72739)

T9C5.240 (NM_114825)

Kip3

N-IIX

Kip3

 

Kinesin-9

KIF9 (AJ132889)

KLP1 (X78589)

 

 

MKLP

(middle clade)

 

Kinesin-10

Nod (M36195)f

KID (AB017430)

KIF22(NM_145588)

T1E22.130 (NM_120315)

 

 

 

 

Kinesin-11

VAB-8 (NM_073662)

KIF26A (XM_138275)

SMY1p (M69021)f

 

 

Divergent

Kinesin-I

 

Kinesin-12

KIF15 (AJ560623)

Xklp2 (X94082)

PaKRP1 (NM_117492)

3g23670 (NM_113271)

JGI_3356g

 

 

MKLP

(upper clade)

 

Kinesin-13

 

MCAK (U11790)

KIF2 (D12644)

3g16060 (NM_112476)

DSK1 (U51680)

MmKif2,

MCAK/Kif2

M

I-Type

KinI

Kinesin-14

NCD (X52814)

KIFC1 (D49544)

KAR3p (M31719)

KATA (D11371)

KCBP (L40358)

C-Terminal Motor

C

C-Type

 

Orphan Kinesinsh

 

 

Orphans

 

Orphans

Ungrouped

 

a Sequences are listed by common name followed by their GenBank ID in parentheses and are color-coded by kingdom: protist sequences are purple, plant sequences are green, animal sequences are red, and those from fungi are blue.

b A list of kinesin sequences and their respective family classification (if known) is actively maintained and exists online at http://www.proweb.org/kinesin//MotorSeqTable.html.

c Dagenbach and Endow, 2004; Goodson et al., 1994; Kim and Endow, 2000; Moore and Endow, 1996

d Hirokawa, 1998

e Lawrence et al., 2002

f Drosophila melanogaster Nod and Saccharomyces cerevisiae SMY1p do not always group with their respective families.  The placement of these two sequences is difficult to attain without carrying out in-depth, careful phylogenetic analyses, and their family placement should be considered tenuous.

g Chlamydomonas reinhardtii sequence from the DOE Joint Genome Institute (http://www.jgi.doe.gov/genomes/).  JGI_3356 is a locus on scaffold 135 at positions 184041-190631.

h Goldstein 1993

 

 

 

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Created 13 September 2004 19:26 GMT
Modified 28 February 2007 15:25 GMT