Subfragment 1

Subfragment 1 (S1) is one of the two heads of myosin produced by proteolytic cleavage of the intact myosin molecule. S1 contains one heavy chain compactly folded into a motor domain and an extended regulatory or light chain domain wrapped by two light chains. The crystal structure of scallop skeletal muscle myosin S1 with essential and regulatory light chains has recently been determined (Houdusse, Kalabokis, Himmel, Szent-Gyorgyi & Cohen 1999 Cell 97, 459-470).

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Created Friday, January 7, 2000