Subfragment 1
Subfragment 1 (S1) is one of the two heads of myosin produced
by proteolytic cleavage of the intact myosin molecule. S1 contains one
heavy chain compactly folded into a motor domain and an extended
regulatory or light chain domain wrapped by two light chains. The crystal structure of
scallop skeletal muscle myosin S1 with essential and regulatory light chains has
recently been determined (Houdusse, Kalabokis, Himmel, Szent-Gyorgyi & Cohen 1999 Cell 97, 459-470).
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Created Friday, January 7, 2000